AlloTec

AlloTec aims to develop a generalized foundational model of allostery mediated protein-protein interactions involved in oncology, inflammation, and neurodegenerative diseases

Challenge: Consider a scenario where two drugs bind to a protein, displaying identical biological activity, yet one blocks protein-protein interactions while the other does not. This situation falls outside the scope of traditional drug discovery and calls for a fundamental understanding of how shifts in protein populations modulate protein-protein interactions.

AlloTec is dedicated to creating innovative computational algorithms and biochemical assays that elucidate how drug binding to specific proteins allosterically modulates protein-protein interactions, leading to foundational understanding of disease mechanisms and development of novel precision medicines.